Liverpool have won their last two home games against Manchester United and the fact that record signing Andy Carroll is on course to make his debut can inspire them to another three points against the Premier League leaders.
Premier League betting odds have Liverpool at 15/8 to beat Manchester United and they are currently unbeaten at home this season against fellow clubs in the top half of the table.
Meanwhile, Liverpool have tasted defeat in just one of their last nine league games at Anfield.
Manchester United are 6/4 to land the spoils and they will be keen to bounce back to winning ways following their defeat at Chelsea.
The good news for Manchester United is that the last nine times they have suffered a Premier League defeat, they have followed up with a victory on eight of these occasions.
Furthermore, they have triumphed in five of their last seven top-flight fixtures.
It is 11/5 that the showdown ends all square, even though only one of the last 21 Premier League meetings between Liverpool and Manchester United have been drawn.
To Score At Any Time
Carroll is believed to have overcome a thigh injury that has delayed his Liverpool debut and there is every chance that he will play some part against Manchester United.
The former Newcastle striker is 7/4 in the Premier League betting to score within the 90 minutes, while Steven Gerrard is 5/2 to make it four goals in as many top-flight games against the Red Devils.
Liverpool’s chances of scoring will also be aided by the fact that Sir Alex Ferguson will have to make do without regular central defensive pairing Nemanja Vidic and Rio Ferdinand, who both miss out.
Manchester United will he hoping that Wayne Rooney can go on a scoring spree and he is 11/10 to strike at any time at Anfield.
A £25 stake on the scorecast of Liverpool beating Manchester United 2-1 and Carroll scoring first would return £1125. New customers can sign up here for a free £25 bet.