The chance to top the Premier League standings for the first time since March should provide Arsenal with that extra bit of encouragement to beat Tottenham in the second north London derby between the pair already this season.
Arsenal have waited a while for their first big Premier League game at the Emirates this season and are 4/6 to beat Tottenham in the football betting.
Spurs have not won away at Arsenal in the Premier League since 1993, while they have only beaten their great adversaries once in the last 21 league meetings.
There are a number of other factors that point towards a home win with Arsenal having won five of their last six games, while they have not lost back-to-back league games at home in 13 years.
Not since 1997 have Arsenal lost more than three home games in a league season and a defeat against Tottenham would already take them to three home defeats after just eight games at the Emirates.
Spurs are 4/1 to beat Arsenal.
Over/Under 2.5 goals
With both teams looking vulnerable in defence, there is a strong possibility that a high-scoring affair will take place.
Just two of the last 13 games between the rivals in all competitions have seen two goals or fewer scored, which means the 8/13 offered on their being at least three goals may prove profitable.
Meanwhile, those looking for a little more value may want to take the 13/8 that at least four goals will be scored.
These bets may also be aided by the fact that potent Spurs marksman Jermain Defoe has returned to the squad after ankle surgery and Tottenham have only kept two cleans sheets in all competitions this season.
Jermaine Jenas has four goals in his last seven games against Arsenal and the injury to Tom Huddlestone may give him a rare start.
Jenas can be backed at 5/1 to score at any time and 16/1 to open the scoring. See the full Arsenal vs Tottenham match betting odds market.