Real Madrid have held a stranglehold over neighbours Atletico Madrid for the whole of the last decade and it can be expected that this will continue as the pair clash in the second leg of their Copa del Rey quarter final.
It has been over ten years since Real Madrid last lost to their rivals, while they have also avoided defeat on their last nine visits to the Vicente Calderon.
Meanwhile, Jose Mourinho is likely to see the tournament as his best chance of obtaining silverware as Real Madrid boss, as proven by the strength of the team he has selected throughout the competition thus far.
With Atletico also needing to attack in order to overturn their 3-1 deficit from the first leg at the Bernabeu. Real Madrid’s betting odds look too large at 4/6 to secure another victory.
Atletico did end a four-match winless streak in all competitions when seeing off Mallorca in their last La Liga game and if this had a major positive impact on their confidence, they could be decent value at 10/3 to beat Real Madrid.
Over/Under 2.5 goals
Despite the abundance of attacking talent present in both squads, perhaps the best betting opportunity is the 13/8 that fewer than three goals are scored.
Chief scoring threat Sergio Aguero will miss out with injury for Atletico, while his regular partner in attack Diego Forlan is still getting games under his belt following a spell on the sidelines.
Similar problems exist at Real Madrid as Gonzalo Higuain is expected to be out for the season and Kaka is building up his match sharpness.
Those wanting a safer bet may prefer accepting the 8/13 that under 3.5 goals are scored in the match.
A £25 stake on Atletico Madrid doing enough to qualify for the Copa del Rey semi finals would return £250. New customers can sign up here for a free £25 bet.