Real Madrid may have lost on their last three visits to Lyon in the Champions League and although they can avoid defeat this time, there is every chance that they may only leave with a draw.
Lyon dumped Real Madrid out of the Champions League at the same second-round stage 12 months ago and are 10/3 in the Champions League betting to do so again.
Key to this end result is likely to be a victory in their home leg and it is 7/2 that they take an advantage to the Bernabeu.
Lyon may be back in fourth in the French top flight at present, but they are currently enjoying a nine-game unbeaten run in all competitions at home.
Furthermore, they have also triumphed in seven of their last 11 home games in the Champions League and lost just once.
Real Madrid will be keen to advance past the last-16 stage of the Champions League for the first time in three seasons and have already won in France in the group stages this year, when beating Auxerre.
Real Madrid’s betting odds are 4/5 to beat Lyon, while the draw, which would put Jose Mourinho’s team in pole position to qualify, is 5/2.
Over/Under 2.5 goals
Lyon have only conceded one goal in their last five home games this season, while their most recent encounters with Real Madrid have tended to be relatively low scoring.
Four of the last five meetings have seen fewer than 2.5 goals scored, while three of these five have witnessed exactly two goals scored.
Football betting odds of 4/5 are available that this season’s meeting at the Stade de Gerland sees a maximum of two goals scored, while it is 5/2 that exactly two goals are scored.
A £25 stake on Lyon drawing 1-1 with Real Madrid would return £137.50. New customers can sign up here for a free £25 bet.