Phil Taylor is the only player to have currently retained the PDC World Championship title and Adrian Lewis looks set to be the latest to fail in a title defence.
Lewis defeated Gary Anderson in the final at Alexandra Palace 12 months ago, but may have difficulty with Terry Jenkins this time around.
Meanwhile, the other quarter final in the evening session looks the most mouth watering on paper as Anderson takes on Simon Whitlock.
Terry Jenkins to beat Adrian Lewis @ 7/4
Jenkins and Lewis are certainly no strangers to each other having squared off 26 times in total and seven times already in 2011.
Lewis has the slight edge having emerged victorious on four of these occasions, alongside knowing what it takes to win the biggest matches at Alexandra Palace having earned the trophy last year.
Clinical finishing is a must for any player with hopes of overall victory and it is hard to improve on Lewis’ 67 per cent checkout figure in his third round success over Wayne Jones.
However, Jenkins also heads into the match in fine form after averaging close to 103 in his triumph in the previous round over Justin Pipe, which was additionally achieved without any especially high finishes.
Jenkins admitted that Pipe’s slow throwing speed actually played to his own strengths and if he can maintain his own pace against Lewis rather than getting drawn into the quicker tempo of the world champion, he could edge through to a second consecutive semi final.
Gary Anderson to beat Simon Whitlock @ 8/15
After a slow start against Colin Lloyd, Anderson began to show some of his old spark, winning one set in just over four minutes with an average above 120.
Whitlock kept his composure after almost blowing a 3-0 lead against Michael Van Gerwin and the length of this match would not have done his broken ankle any good.
Anderson has also won his last eight matches with Whitlock, with all of these successes coming in 2011.
All of these victories have been tight and so Anderson to prevail 5-3 looks the standout option in the correct score market at 9/2, while the Scot is also likely to hit the most 180s in the match, which can be backed at 4/5.