For several weeks it had been thought that Super Tuesday Part 2 could be the downfall of Marco Rubio, and that proved to be exactly the case as the Floridian dropped out of the Republican nominee battle after another dismal night at the polls.
The death-knell came at home, with the Sunshine State handing Donald Trump 45 per cent of the vote to claim the winner-takes-all 99 delegates.
Rubio languished well behind in second with 27 per cent, and promptly called time on his campaign.
Trump also prevailed in Illinois and North Carolina, while John Kasich came out tops in his home state of Ohio.
Former real estate mogul Trump is 2/7 favourite to be named Republican nominee, and requires just 54 per cent of the remaining delegates to do so before July.
Over at the Democrat fight, Hillary Clinton strengthened her vice-like grip on the race for the White House after dominating last night as Bernie Sanders failed to build on his Michigan win.
The former Secretary of State notched sizeable wins in Florida and North Carolina, while Rust Belt states Ohio and Illinois failed to follow Michigan’s lead for Sanders.
What it all means is that Clinton is at her shortest odds yet to be the President of the United States, with her price clipped from 8/15 to 4/9 overnight.
Trump remains very much her most likely challenger, with the bookies 5/2 on the former US Apprentice host claiming the White House.
Clinton to beat Trump in the upcoming election also saw a fall, from evens last week to 8/11.
With each passing State, so Trump and Clinton extend their chances, and it seems only a seismic error from either of the pair can stop them.
All Odds and Markets are correct as of the date of publishing.