Both Chile and Switzerland managers make changes to winning teams for their match at the top of Group H, which kicks off at 3pm.
Marcelo Bielsa and Ottmar Hitzfeld recall a star striker each with Humberto Suazo coming in for Chile and Alexander Frei up front for Switzerland.
Jorge Valdivia, who picked up a knock against Honduras, and Eren Derdiyok are the players to make way.
The other swap for the South Americans is Gonzalo Jara in place of Rodrigo Millar.
Hitzfeld welcomes back Valon Behrami who will start on the wing instead of Tranquillo Barnetta, while Steve Von Bergen continues in place of injured Philippe Senderos.
Alexis Sanchez was superb against Honduras and seems a good bet, at5/1, to open his World Cup account with the first goal here.
The Swiss put on a classic defensive display to deny Spain and another clean sheet for them is 9/4.
The teams in full:
Bravo (Captain), Ponce, Isla, Medel, Carmona, Vidal, Jara, Fernandez, Suazo, Sanchez, Beausejour
Benaglio, Lichtsteiner, Senderos, Grichting, Ziegler, Huggel, Barnetta, Inler (Captain), Fernandes, Nkufo, Derdiyok