In what is being touted as one of the biggest matches in Premier League history, every action of Manchester City and Manchester United players will come under scrutiny tonight.
That being the case, Ladbrokes have opened a book on an abundance of conceivable activities that may take place within the game.
Sir Alex Ferguson has himself declared it the biggest meeting of the clubs in his 26-year Old Trafford tenure, and the stage looks set for an unforgettable fixture to play out at Eastlands.
Drama is certain to encapsulate this derby from the first whistle to the last, with the stakes never higher as the winner takes the mantle as clear favourites for the Premier League title.
There are 3/1 odds available about the last goal of the match occurring in injury time, and as this has been the case in three of the past five league meetings between these two, many punters will invest in the possibility of it occurring again.
At the shortest price of the match specials available to bet on meanwhile, is a player to reveal a T-shirt message as part of a goal celebration at 5/2.
Mario Balotelli revealed a shirt sporting the message “Why Always Me?” when scoring the first of his Old Trafford brace earlier in the season, and it appears likely that his example could be followed tonight.
Also, in a game where emotions are sure to run high, 6/1 odds for a manager to be sent to the stands are tempting, especially considering neither boss is particularly conservative.
Often controversial referee Howard Webb will take charge of the match, and has a reputation for making brave, and sometimes game-altering decisions.
With this in mind, it could also be worth taking on the 6/1 price about the final goal of the game being scored from the penalty spot, particularly in light of the unerring nature of Wayne Rooney and Sergio Aguero from 12 yards out.