Estonia top Group C after starting their campaign early against the Faroe Islands in August, but are 8/1 to beat Italy and increase their lead at the top of the table.
Italy suffered a shambolic World Cup campaign finishing bottom of their group, and coach Cesare Prandelli is looking to inject youth and enthusiasm into a new-look Italy side.
Prandelli is without Gianluigi Buffon and has selected just one defender with more than three caps as he attempts to rebuild the Italian team, starting with the game in Tallinn, where they are 4/11 to win.
Daniele De Rossi and Andrea Pirlo keep their places in the team and the 125 caps that the two have amassed will be invaluable as Prandelli looks to them to influence the rookies that have entered the team.
Andres Oper, the Baltic nation’s all time leading scorer will miss the game with injury.
Manager Tarmo Ruutli has replaced him with striker Vjatselav Zahovaiko as Ruutli looks to take advantage of the Italian transition.
Estonia will also be able to take heart after only going down by the one goal to Brazil earlier in the year and will provide Italy with a sterner test than their 8/1 odds suggest.
“It’s clear that we aren’t favourites but that doesn’t mean there will be no expectation on us,” said Ruutli, “Surprises happen. Why not this time?”
Italy have won all four games these two sides have contested with Estonia only managing the one goal and conceding 11, but Estonia will hope they can exploit Italy’s inexperienced defence, they are 10/3 as a team to score first.
Anything less than a win for Italy would be disastrous for team morale. See the full Estonia vs Italy football betting market here.