While Real Madrid eased into the Champions League semi-finals this week, Barcelona went crashing out.
Only a La Liga title can save their season now – but they must win El Clasico this weekend.
Barca sit three points behind Real, and Zinedine Zidane’s side have a game in hand too versus mid-table Celta Vigo.
So victory for the hosts at the Bernabeu this Sunday would in all likelihood open up what would effectively be an insurmountable nine-point lead.
A lot of that is down to the fact that Lionel Messi and co have failed to win three of their last four games in all competitions, while their away record reads just two wins from six.
Real meanwhile, have lost just three competitive games on home soil in 25 months.
Barcelona ran out 4-0 winners in this fixture last year, helped in no small part by Neymar’s goal to make it 2-0 shortly before the break.
But the Brazilian is suspended this weekend, reducing Luis Enrique’s MSN attack to simply, MS.
Real meanwhile are sweating on the fitness of Gareth Bale, who is in a race against time to be in the squad.
That romp for Barca last term is the only time in 21 El Clasicos that we have seen a clean sheet.
Cristiano Ronaldo arrives having scored a hat-trick to dump Bayern Munich out of the Champions League in midweek, and the Portuguese ace leads the first goalscorer betting at 10/3.
While Ronaldo has 16 goals in 29 games versus Barca, Lionel Messi can boast 21 goals from 33 meetings.
The Argentine is 9/2 to score first, having netted 45 times from 45 appearances this term.
Luis Suarez and Karim Benzema are each 5/1 to bag the opener.
But the Spaniard really loves a 90th minute winner, and it’s 16/1 for Ramos to score the game’s final goal once again.
It all kicks-off at 19:45 on Sunday, and you can catch all the action on Ladbrokes.com via our live streaming service!
All Odds and Markets are correct as of the date of publishing